Recombinant Human ANKRD17 protein


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Cat.No.:  PE-2570
Product Name:  Recombinant Human ANKRD17 protein
Background:  Could play pivotal roles in cell cycle and DNA regulation (PubMed:19150984). Involved in innate immune defense against viruse by positively regulating the viral dsRNA receptors DDX58 and IFIH1 signaling pathways (PubMed:22328336). Involves in NOD2- and NOD1-mediated responses to bacteria suggesting a role in innate antibacterial immune pathways too (PubMed:23711367). Target of enterovirus 71 which is the major etiological agent of HFMD (hand, foot and mouth disease) (PubMed:17276651). Could play a central role for the formation and/or maintenance of the blood vessels of the circulation system.
Applications:  Western blot; ELISA
Storage:  Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles.
Appearance:  Liquid
Species:  Human
Formulation:  pH: 8.00; Constituents: 0.31% Glutathione, 0.79% Tris HCl
Alternative Names:  ANKRD 17/ANKRD17/Ankyrin repeat domain protein 17
Tag:  GST
Amino Acid Sequence:  MEKATVPVAAATAAEGEGSPPAVAAVAGPPAAAEVGGGVGGSSRARSASS PRGMVRVCDLLLKKKPPQQQHHKAKRNRTCRPPSSSESSSDSDNSGGGGG GGGGGGGGGGTSSNNSEEEEDDDDEEEEVSEVESFILDQDDLENPMLETA SKLLLSGTADGADLRTVDPETQARLEALLEAAGIGKLSTADGKAFADPEV LRRLTSSVSCALDEAAAALTRMRAESTANAGQSDNRSLAEACSEGDVNAV RKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG DITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVV KVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEF KESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVA RLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEG YTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVA DFLIKAGADIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTA LTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLI SKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTM LIEAAKGGHTSVVCYLLDYPNNLLSAPPPDVTQLTPPSHDLTDNIFPRLV C
Sequence Similarities:  Contains 25 ANK repeats.Contains 1 KH domain.
Expression System:  Wheat germ
Post Translational Modifications:  Phosphorylated by CDK2.
Protein Length:  Full length protein; 1 to 751
Warning:  This product is for research use only. Not for use in diagnostic or therapeutic procedures.

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