| Cat.No.: | PE-2154 |
| Product Name: | Recombinant Human A3H protein |
| Background: | ARP10 belongs to the cytidine and deoxycytidylate deaminase family. It is a poorly expressed deaminase that is ineffective at inhibiting retroviral replication. ARP10 has DNA deaminase (cytidine deaminase) activity but is not able to mediate G-to-A hypermutation in newly synthesized retroviral DNA. It is present at low level in 293T cells. It is considered an unstable protein, suggesting that it may be degraded by the proteasome (at protein level). Weakly expressed in testis, ovary, fetal liver and skin. There are two named isoforms. ARP10 from old world monkeys has retained its antiviral activity, while it is lost in other primates. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. |
| Applications: | Western blot; ELISA |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Species: | Human |
| Formulation: | pH: 8.00; Constituents: 0.31% Glutathione, 0.79% Tris HCl |
| Alternative Names: | A3H/APOBEC related protein 10/APOBEC3H |
| Tag: | GST |
| Amino Acid Sequence: | MALLTAETFRLQFNNKRRLRRPYYPRKALLCYQLTPQNGSTPTRGYFENK KKCHAEICFINEIKSMGLDETQCYQVTCYLTWSPCSSCAWELVDFIKAHD HLNLGIFASRLYYHWCKPQQKGLRLLCGSQVPVEVMGFPEFADCWENFVD HEKPLSFNPYKMLEELDKNSRAIKRRLERIKS |
| Expression System: | Wheat germ |
| Protein Length: | Full length protein; 1 to 182 |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0374 | APOBEC3D Polyclonal Antibody | Inquiry |
| EAb-0375 | APOBEC2 Polyclonal Antibody | Inquiry |
| EAb-0393 | APOBEC3G Polyclonal Antibody | Inquiry |
| EAb-0403 | APOBEC3C Polyclonal Antibody | Inquiry |
| ◆ Cell Lines | ||
| CL-0388 | Human APTX Knockout Cell Line 11bp deletion | Inquiry |
| Related Gene / Proteins | |||
| AP-2 | Ape1 | APOBEC2 | APOBEC3A |
| APOBEC3B | APOBEC3C | APOBEC3D | APOBEC3F |
| APOBEC3G | APOBEC3H | APOBEC4 | APTX |
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