| Cat.No.: | PE-2054 |
| Product Name: | Recombinant Human KMT4 / Dot1L protein |
| Background: | Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA. |
| Applications: | SDS-PAGE |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Molecular Weight: | 74 kDa including tags |
| Purity: | > 95 % SDS-PAGE. |
| Species: | Human |
| Accession#: | Q8TEK3 |
| Alternative Names: | Disrupter of telomere silencing protein 1/DOT 1/DOT1 |
| Amino Acid Sequence: | GEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDL KLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTR PSTGLLRHILQQVYNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEI KMTDDDLFVDLGSGVGQVVLQVAAATNCKHHYGVEKADIPAKYAETMDRE FRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFVNNFAFGPEVDH QLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLKG SVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRESKS NAATPTKGPEGKVAGPADAPMDSGAEEEKAGAATVKKPSPSKARKKKLNK KGRKMAGRKRGRPKK |
| Sequence Similarities: | Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.Contains 1 DOT1 domain. |
| Expression System: | E. coli |
| Protein Length: | Protein fragment; 2 to 416 |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
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