Activation of caspases plays a central role in apoptosis. The Red Active Caspase-8 Staining Kit provides a convenient means for detecting activated caspase-8 in; Living cells. The assay utilizes a caspase-8 inhibitor IETD-FMK conjugated to sulfo-rhodamine (Red-IETD-FMK) as the fluorescent marker. Red-IETD-FMK is cell permeable, nontoxic, and irreversibly binds to activated caspase-8 in apoptotic cells.
Simple one-step procedure; takes only 1-2 hours; Fast and convenient; The fluorescence label allows detection of activated caspase-8 in apoptotic cells