Product Overview :
Simple & convenient protocol.
Can detect Plasmin activity as low as 10 ng in a variety of samples.
Kit contains all necessary reagents for measuring plasmin activity.
Description :
Plasmin (EC 3.4.21.7) is a serine protease occurring in plasma as plasminogen. Upon activation via cleavage by plasminogen activators; plasmin solubilizes fibrin clots and activates and/or degrades compounds of the coagulation and complement systems. Plasminogen-Plasmin system has also been implicated in a wide variety of physiologic and pathologic processes, including tumor growth, invasion and metastasis. Plasmin activity assay kit utilizes the ability of Plasmin to proteolytically cleave a synthetic substrate and release a fluorophore, AMC, which can be easily quantified by fluorescence microplate readers. This assay kit is simple, rapid and can detect Plasmin activity as low as 10 ng in a variety of samples.
Applications :
Detect the activity of Plasmin in plasma
Usage :
For Research Use Only! Not For Use in Humans
Kit Components :
• Plasmin Assay Buffer
• Plasmin Dilution Buffer
• Plasmin Enzyme Standard (1 mg/ml)
• Plasmin Substrate
Detection method :
Fluorescence (Ex/Em = 360/450 nm)
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